Purity
> 95% as determined by SDS-PAGE
Buffer
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization
Introduction
Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system.
Keywords
Fibroblast growth factor receptor 1; FGFR1; FLT-2; CD331
Citations
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Andre, F; Cortes, J; et al. Rationale for targeting fibroblast growth factor receptor signaling in breast cancer. BREAST CANCER RESEARCH AND TREATMENT 150:1-8(2015).
Waddell, N; Pajic, M; et al. Whole genomes redefine the mutational landscape of pancreatic cancer. NATURE 518:495-501(2015).
COA
Certificate of Analysis
