Anti-UBE2S Polyclonal Antibody (CABT-L2091) Knockout Validated

Rabbit Anti-Human UBE2S Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Native Human UBE2S
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.2-2 ug/ml; 1:250-2500
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type 293T cell lysate. Lane 2: UBE2S knockout 293T cell lysate. Predicted MW: 24kd, Observed MW: 30kd

Target


Alternative Names
E2-EPF; Ubiquitin Carrier Protein; Ubiquitin-Protein Ligase; Ubiquitin-protein ligase S
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adaptive Immune System; Antigen processing: Ubiquitination & Proteasome degradation; Class I MHC mediated antigen processing & presentation; Immune System; Ubiquitin mediated proteolysis;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


ZHEN, M; HEINLEIN, R; et al. THE UBC-2 GENE OF CAENORHABDITIS-ELEGANS ENCODES A UBIQUITIN-CONJUGATING ENZYME INVOLVED IN SELECTIVE PROTEIN-DEGRADATION. MOLECULAR AND CELLULAR BIOLOGY 13:1371-1377(1993).
Tiwari, S; Weissman, AM; et al. Endoplasmic reticulum (ER)-associated degradation of T cell receptor subunits - Involvement of ER-associated ubiquitin-conjugating enzymes (E2s). JOURNAL OF BIOLOGICAL CHEMISTRY 276:16193-16200(2001).

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