Anti-TLR5 Polyclonal Antibody (CABT-L2179) Knockout Validated

Rabbit Anti-Human TLR5 (Asn46~Ala205) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment corresponding to human TLR5 (Asn46~Ala205)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-5 ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type A549 cell lysate. Lane 2: TLR5 knockout A549 cell lysate. Predicted MW: 97kd, Observed MW: 105kd
Figure. Western Blot. Sample. Lane1: Human A549 Cells; Lane2: Human Hela Cells.

Target


Alternative Names
CD285; SLEB1; TIL3; Toll/Interleukin-1 Receptor-Like Protein 3
Entrez Gene ID
UniProt ID

Product Background


Pathway
Immune System; Inflammatory bowel disease (IBD); Innate Immune System; Legionellosis; MyD88 cascade initiated on plasma membrane; Pathogenic Escherichia coli infection; Regulation of toll-like receptor signaling pathway; Salmonella infection;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Zhang, LL; Che, CY; et al. TLR-mediated Induction of Proinflammatory Cytokine IL-32 in Corneal Epithelium. CURRENT EYE RESEARCH 38:630-638(2013).
Remer, KA; Brcic, M; et al. Human monocytoid cells as a model to study Toll-like receptor-mediated activation. JOURNAL OF IMMUNOLOGICAL METHODS 313:1-10(2006).

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