Anti-SPTLC1 Polyclonal Antibody (CABT-L2216) Knockout Validated

Rabbit Anti-Human SPTLC1 (Asp143~Leu473) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Mouse
Immunogen
Recombinant fragment corresponding to human SPTLC1 (Asp143~Leu473)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-2 ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type Jurkat cell lysate. Lane 2: SPTLC1 knockout Jurkat cell lysate. Predicted MW: 53kd, Observed MW: 55kd
Figure. Western Blot. Sample. Lane1: Mouse Liver Tissue; Lane2: Mouse Lung Tissue; Lane3: Mouse Brain Tissue; Lane4: Human Jurkat Cells.

Target


Alternative Names
HSAN; HSAN1; HSN1; LBC1; LCB1; SPT1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Ceramide biosynthesis; Metabolic pathways; Metabolism; Metabolism of lipids and lipoproteins; Sphingolipid Metabolism; Sphingolipid de novo biosynthesis; Sphingolipid metabolism; Sphingosine biosynthesis;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Hornemann, T; Wei, Y; et al. Is the mammalian serine palmitoyltransferase a high-molecular-mass complex?. BIOCHEMICAL JOURNAL 405:157-164(2007).

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