Anti-PSMD9 Polyclonal Antibody (CABT-L2288) Knockout Validated

Rabbit Anti-Human PSMD9 (Ser2~Arg223) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Mouse
Immunogen
Recombinant fragment corresponding to human PSMD9 (Ser2~Arg223)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-5 ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type A549 cell lysate. Lane 2: PSMD9 knockout A549 cell lysate. Predicted MW: 24, 22, 13kd, Observed MW: 30kd
Figure. Western Blot. Sample. Lane1: Human Liver Tissue; Lane2: Mouse Spleen Tissue; Lane3: Mouse Heart Tissue; Lane4: Human A549 Cells; Lane5: Mouse Placenta Tissue.

Target


Alternative Names
Rpn4; p27; 26S proteasome regulatory subunit p27; 26S proteasome non-ATPase regulatory subunit 9
Entrez Gene ID
UniProt ID

Product Background


Pathway
AMER1 mutants destabilize the destruction complex; APC truncation mutants are not K63 polyubiquitinated; APC truncation mutants have impaired AXIN binding; APC/C-mediated degradation of cell cycle proteins; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdc20 mediated degradation of mitotic proteins; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell c

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Watanabe, TK; Saito, A; et al. cDNA cloning and characterization of a human proteasomal modulator subunit, p27 (PSMD9). GENOMICS 50:241-250(1998).

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