Anti-IL7R Polyclonal Antibody (CABT-L2018) Knockout Validated

Rabbit Anti-Human IL7R (Lys173~Ala260) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment corresponding to human IL7R (Lys173~Ala260)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 1-5 ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type K562 cell lysate. Lane 2: IL7R knockout K562 cell lysate. Predicted MW: 51, 34, 29kDa, Observed MW: 60kDa
Figure. Western Blot. Sample. Lane1: Human Lung Tissue; Lane2: Human K562 Cells; Lane3: Human Jurkat Cells.

Target


Alternative Names
CDW127; CD127; IL-7R-Alpha
Entrez Gene ID
UniProt ID

Product Background


Pathway
Cytokine Signaling in Immune system; Cytokine-cytokine receptor interaction; FoxO signaling pathway; Hematopoietic cell lineage; IL-7 Signaling Pathway; Immune System; Interleukin-7 signaling; Jak-STAT signaling pathway;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Haralambieva, IH; Ovsyannikova, IG; et al. Associations between single nucleotide polymorphisms and haplotypes in cytokine and cytokine receptor genes and immunity to measles vaccination. VACCINE 29:7883-7895(2011).
Buckley, RH; Win, CM; et al. Post-Transplantation B Cell Function in Different Molecular Types of SCID. JOURNAL OF CLINICAL IMMUNOLOGY 33:96-110(2013).

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