Anti-GZMA Polyclonal Antibody (CABT-L2067) Knockout Validated

Rabbit Anti-Human GZMA (Ile29~Val260) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Mouse
Immunogen
Recombinant fragment corresponding to human GZMA (Ile29~Val260)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-2 ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type Jurkat cell lysate. Lane 2: GZMA knockout Jurkat cell lysate. Predicted MW: 29kDa, Observed MW: 27kDa
Figure. Western Blot. Sample. Mouse Kidney Tissue.

Target


Alternative Names
CTLA3; HFSP; HF; H factor; Granzyme 1; Fragmentin-1
Entrez Gene ID
UniProt ID

Product Background


Pathway
IL12-mediated signaling events; Neuroactive ligand-receptor interaction;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


van Dommelen, SLH; Sumaria, N; et al. Perforin and granzymes have distinct roles in defensive immunity and immunopathology. IMMUNITY 25:835-848(2006).
Bade, B; Boettcher, HE; et al. Differential expression of the granzymes A, K and M and perforin in human peripheral blood lymphocytes. INTERNATIONAL IMMUNOLOGY 17:1419-1428(2005).

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