Anti-ABCD2 Polyclonal Antibody (CABT-L2280) Knockout Validated

Rabbit Anti-Human ABCD2 (Lys501~Leu695) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Mouse
Immunogen
Recombinant fragment corresponding to human ABCD2 (Lys501~Leu695)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.2-2 ug/ml; 1:250-2500
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type 293T cell lysate. Lane 2: ABCD2 knockout 293T cell lysate. Predicted MW: 83kd, Observed MW: 75kd
Western Blot. Sample. Human 293T cell lysate.
Western Blot. Sample. Mouse Spleen lysate.

Target


Alternative Names
ABC-D2; ABC39; ALDL1; ALDR; ALDRP; hALDR
Entrez Gene ID
UniProt ID

Product Background


Pathway
ABC transporters; ABC-family proteins mediated transport; ABCA transporters in lipid homeostasis; Nuclear receptors in lipid metabolism and toxicity; Peroxisome; Transmembrane transport of small molecules;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Liu, XX; Liu, JJ; et al. ABCD2 identifies a subclass of peroxisomes in mouse adipose tissue. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 456:129-134(2015).
Park, CY; Kim, HS; et al. ABCD2 Is a Direct Target of beta-Catenin and TCF-4: Implications for X- Linked Adrenoleukodystrophy Therapy. PLOS ONE 8:-(2013).

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