ELISA; Matched pair Antibody available for Amanitin[BSA], Amanitin Antibody(Cat.# CABT-L3113)
Format
Liquid
Concentration
Batch dependent - please inquire should you have specific requirements.
Buffer
0.01M PBS, pH 7.2
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Antigen Description
Amanitin is a bicyclic octapeptide which belongs to a large group of protoplasmic mushroom toxins known as amatoxins. Among the mushroom species is the green death cap mushroom (Amanita phalloides) as well as Amanita verna, Amanita virosa, Amanita bisporigera, Amanita ocreata, Amanita tenuifolia, Galerina and Conocybe filaris. These mushroom species produce α-amanitin in amounts sufficient to poison an adult person with liver damage and fatal outcome (LD50, p.o. humans; 0.1mg/kg). α-Amanitin kills cells by inhibiting RNA polymerase II (Pol II) and shutting down gene transcription.
Keywords
Amanitin; alpha Amanitin
Citations
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