Molecular Weight
app. 65 kDa
Alternative Names
allopurinol; 1H-Pyrazolo[3,4-d]pyrimidin-4-ol; Zyloprim; Lopurin
Purity
chromatography, dialysis
Concentration
1 mg/mL, conjugation ratio is app. 1:10 - 1:40.
Preservative
0.05% sodium azide
Introduction
Allopurinol is a structural isomer of hypoxanthine. Allopurinol inhibits xanthine oxidase, an enzyme that converts oxypurines to uric acid. By blocking the production of uric acid, this agent decreases serum and urine concentrations of uric acid, thereby providing protection against uric acid-mediated end organ damage in conditions associated with excessive production of uric acid, i.e. the massive cell lysis associated with the treatment of some malignancies.
Antigen Description
Allopurinol, covalently linked to biotinylated human serum albumin
Keywords
drug-HSA-Biotin conjugate, drug-conjugate, Allopurinol HSA-Biotin conjugate
Citations
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