Molecular Weight
app. 65 kDa
Alternative Names
N-Acetyl-L-cysteine; acetylcysteine; N-Acetylcysteine; mercapturic acid
Purity
chromatography, dialysis
Concentration
1 mg/mL, conjugation ratio is app. 1:10 - 1:40.
Preservative
0.05% sodium azide
Introduction
Acetylcysteine is a synthetic N-acetyl derivative of the endogenous amino acid L-cysteine, a precursor of the antioxidant enzyme glutathione. Acetylcysteine regenerates liver stores of glutathione. This agent also reduces disulfide bonds in mucoproteins, resulting in liquification of mucus. Some evidence suggests that acetylcysteine may exert an anti-apoptotic effect due to its antioxidant activity, possibly preventing cancer cell development or growth. In addition, acetylcysteine has inhibited viral stimulation by reactive oxygen intermediates, thereby producing antiviral activity in HIV patients.
Antigen Description
Acetylcysteine, covalently linked to human serum albumin
Keywords
drug-HSA conjugate, drug-conjugate, Acetylcysteine HSA conjugate
Citations
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