The ZSCAN4 gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem (ES) cells, namely, defying cellular senescence and maintaining normal karyotype for many cell divisions in culture (Zalzman et al., 2010 [PubMed 20336070]).[supplied by OMIM, May 2010]
Function
DNA binding; metal ion binding; sequence-specific DNA binding transcription factor activity
Synonyms
ZSCAN4; zinc finger and SCAN domain containing 4; ZNF494; zinc finger and SCAN domain-containing protein 4; zinc finger protein 494
Citations
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