The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. [provided by RefSeq, Jul 2008]
Function
double-stranded RNA binding; enzyme binding; poly(A) RNA binding; protein binding; zinc ion binding
Synonyms
ZNF346; zinc finger protein 346; JAZ; Zfp346; just another zinc finger protein; double-stranded RNA-binding zinc finger protein JAZ
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