Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A12 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Aug 2008]
Function
metal ion transmembrane transporter activity
Synonyms
SLC39A12; solute carrier family 39 (zinc transporter), member 12; ZIP-12; LZT-Hs8; bA570F3.1; zinc transporter ZIP12; zrt- and Irt-like protein 12; solute carrier family 39 member 12; LIV-1 subfamily of ZIP zinc transporter 8; solute carrier family 39 (metal ion transporter), member 12
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