General Notes
This product (Catalog No. CABT-BL3824) is a rabbit-derived polyclonal antibody raised against human YIPF4, targeting the amino acid region 1–113 of the protein. This antibody exhibits cross-reactivity with Human YIPF4 from mouse and rat. It has been affinity purified by Protein A. YIPF4 (Yip1 Domain Family Member 4) is a multi-pass membrane protein that belongs to the Yip1 domain family, which is involved in intracellular membrane trafficking, particularly within the early secretory pathway. It is primarily localized to the endoplasmic reticulum (ER) and Golgi apparatus, where it participates in the organization and function of vesicle-mediated transport systems. YIPF4 is thought to play a role in ER–Golgi vesicular trafficking and membrane organization, potentially acting as a scaffold or regulatory component that ensures proper protein sorting and transport. Members of the YIPF family often function in complexes that regulate COPII-mediated vesicle formation and Golgi integrity. Although the precise molecular mechanisms of YIPF4 are not fully defined, it is broadly expressed and considered important for maintaining cellular secretory pathway homeostasis.
CABT-BL3824 is suitable for use in Western blot (WB) (1:1,000–1:4,000), IHC (1:50–1:500), IF/ICC (1:50–1:500) applications.
CABT-BL3824 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.