Human WFDC1 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-WFDC1/PS20 antibody

Target

WFDC1 / PS20

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Gene ID

58189

UniProt ID

Q9HC57

Antigen Description

This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. This gene is downregulated in many cancer types and may be involved in the inhibition of cell proliferation. The encoded protein may also play a role in the susceptibility of certain CD4 memory T cells to human immunodeficiency virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Function

molecular_function; peptidase inhibitor activity; serine-type endopeptidase inhibitor activity;

Synonyms

WFDC1; WAP four-disulfide core domain 1; WAP four-disulfide core domain protein 1; PS20; ps20 growth inhibitor; prostate stromal protein ps20; WAP four-disulfide core domain 1 homolog;