This gene encodes a protein subunit of the ESCRT-I complex (endosomal complexes required for transport), which functions in the transport and sorting of proteins into subcellular vesicles. This complex can also be hijacked to facilitate the budding of enveloped viruses from the cell membrane. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Function
protein binding;
Synonyms
VPS28; vacuolar protein sorting 28 homolog (S. cerevisiae); vacuolar protein sorting 28 (yeast); vacuolar protein sorting-associated protein 28 homolog; H-Vps28; ESCRT-I complex subunit VPS28; yeast class E protein Vps28p homolog; MGC60323;
Citations
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