The protein encoded by this gene is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea. The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets. This protein is also involved in the development of the neural plate. [provided by RefSeq, Sep 2011]
Synonyms
VANGL2; VANGL planar cell polarity protein 2; LPP1; LTAP; STB1; STBM; STBM1; vang-like protein 2; strabismus 1; van Gogh-like protein 2; loop-tail protein 1 homolog; loop-tail-associated protein; vang-like 2 (van gogh, Drosophila);
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