Product Overview
Blocking/Immunizing peptide for anti-USP16 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Function
cysteine-type endopeptidase activity; histone binding; transcription coactivator activity; ubiquitin binding; ubiquitin thiolesterase activity; ubiquitin-specific protease activity; zinc ion binding;
Synonyms
USP16; ubiquitin specific peptidase 16; UBPM; UBP-M; ubiquitin carboxyl-terminal hydrolase 16; ubiquitin thioesterase 16; deubiquitinating enzyme 16; ubiquitin thiolesterase 16; ubiquitin specific protease 16; ubiquitin-processing protease UBP-M; ubiquitin-specific processing protease 16; ubiquitin-specific-processing protease 16;
Citations
Publication ()
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COA
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