Anti-UGT2B17 (internal region) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A KLH conjugated synthetic peptide selected from the center region of Human UGT2B17.

Conjugate

Application Notes

ICC/IF: 5μg/ml
WB: 1:50-1:100
ELISA: 1:1000

Alternative Names

UGT2B17; UDP glucuronosyltransferase 2 family, polypeptide B17; UDP glycosyltransferase 2 family, polypeptide B17; UDP-glucuronosyltransferase 2B17; C19 steroid specific UDP glucuronosyltransferase; C19 steroid specific UDPGT; UDB17; UDP glucuronosyltransferase 2B17; UDPGT 2B17; C19-steroid-specific UDPGT; UDP glycosyltransferase 2 family, member B17; UDP-glucuronyltransferase, family 2, beta-17; C19-steroid-specific UDP-glucuronosyltransferase; UDPGT2B17;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the uridine diphosphoglucuronosyltransferase protein family. The encoded enzyme catalyzes the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a diverse array of substrates including steroid hormones and lipid-soluble drugs. This process, known as glucuronidation, is an intermediate step in the metabolism of steroids. Copy number variation in this gene is associated with susceptibility to osteoporosis.

Pathway

Ascorbate and aldarate metabolism, organism-specific biosystem; Ascorbate and aldarate metabolism, conserved biosystem; Ascorbate biosynthesis, animals, glucose-1P => ascorbate, organism-specific biosystem; Ascorbate biosynthesis, animals, glucose-1P => ascorbate, conserved biosystem; Biological oxidations, organism-specific biosystem; Drug metabolism - cytochrome P450, organism-specific biosystem; Drug metabolism - cytochrome P450, conserved biosystem; Drug metabolism - other enzymes, org