Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008]
Function
transferase activity
Synonyms
TRMT12; tRNA methyltransferase 12 homolog (S. cerevisiae); TYW2; TRM12; tRNA wybutosine-synthesizing protein 2 homolog; tRNA-yW synthesizing protein 2; tRNA-yW-synthesizing protein 2; tRNA methyltranferase 12 homolog; homolog of yeast tRNA methyltransferase; alpha-amino-alpha-carboxypropyl transferase TYW2; tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase
Citations
Publication ()
Have you cited CDBP6367 in a publication? Let us know and earn a reward for your research.
Creative Diagnostics products are for RESEARCH USE ONLY, please make sure your review is research based.
Required fields are marked with *
Terms and conditions:
We will select high-quality review customers and offer a $30 coupon for your next purchase.
All product reviews must be submitted in the English language.
Creative Diagnostics will not share any personal information of applicants, and all information will be treated with strict confidentiality and will not be sold or disclosed to a third party.
COA
Publication 
Loading ......
