Wybutosine (yW) is a hypermodified guanosine found in phenylalanine tRNA adjacent to the anticodon that stabilizes codon-anticodon interactions in the ribosome. In yeast, the homolog of this gene is essential for the synthesis of wybutosine. [provided by RefSeq, Dec 2012]
Function
4 iron, 4 sulfur cluster binding; FMN binding; iron ion binding; lyase activity; oxidoreductase activity
Synonyms
TYW1; tRNA-yW synthesizing protein 1 homolog (S. cerevisiae); TYW1A; RSAFD1; YPL207W; S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase; tRNA-yW synthesizing protein 1 homolog A; tRNA wybutosine-synthesizing protein 1 homolog; radical S-adenosyl methionine and flavodoxin domains 1; radical S-adenosyl methionine and flavodoxin domain-containing protein 1
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