This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel, and may play a role in kidney tumorigenesis. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Function
chloride channel activity; protein binding
Synonyms
TTYH2; tweety family member 2; C17orf29; protein tweety homolog 2; hTTY2; tweety homolog 2
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