Human TARBP2 blocking peptide (CDBP3041)

Synthetic Human TARBP2 blocking peptide for BL

Product Overview
Blocking peptide for anti-TRBP1 antibody
Target
TRBP1
Nature
Synthetic
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not suitable for human or animal consumption.
Procedure
None
Format
Liquid
Concentration
200 μg/ml
Size
50 μg
Buffer
PBS containing 0.02% sodium azide
Preservative
0.02% Sodium Azide
Storage
Store at -20℃, stable for one year.
UniProt ID
Antigen Description
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene. [provided by RefSeq, Jul 2008]
Function
double-stranded RNA binding; protein binding; protein homodimerization activity; siRNA binding;
Synonyms
TARBP2; TAR (HIV-1) RNA binding protein 2; Tar (HIV 1) RNA binding protein 2; RISC-loading complex subunit TARBP2; TAR RNA binding protein 2; TAR RNA-binding protein 2; TAR (HIV) RNA binding protein 2; TAR (HIV) RNA-binding protein 2; TAR (HIV) RNA-binding protein TRBP1; trans-activation responsive RNA-binding protein; trans-activation-responsive RNA-binding protein; LOQS; TRBP; TRBP1; TRBP2;

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References


Richter, SN; Palu, G; et al. Inhibitors of HIV-1 Tat-mediated transactivation. CURRENT MEDICINAL CHEMISTRY 13:1305-1315(2006).
Chaloin, O; Peter, JC; et al. The N-terminus of HIV-1 Tat protein is essential for Tat-TAR RNA interaction. CELLULAR AND MOLECULAR LIFE SCIENCES 62:355-361(2005).

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