This product (Catalog No. CABT-BL3535) is a rabbit-derived polyclonal antibody raised against human TBCA. This antibody exhibits cross-reactivity with TBCA from mouse. It has been affinity purified by Protein A. The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. CABT-BL3535 is suitable for use in Western blot (WB) (1:200–1:1,000), IHC (1:100–1:200) applications. CABT-BL3535 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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