Tapasin, or TAPBP (MIM 601962), is a member of the variable-constant Ig superfamily that links major histocompatibility complex (MHC) class I molecules to the transporter associated with antigen processing (TAP; see MIM 170260) in the endoplasmic reticulum (ER). The TAPBP gene is located near the MHC complex on chromosome 6p21.3. TAPBPL is a member of the Ig superfamily that is localized on chromosome 12p13.3, a region somewhat paralogous to the MHC.[supplied by OMIM, Mar 2008]
Synonyms
TAPBPL; TAP binding protein-like; tapasin-related protein; FLJ10143; TAPBP R; TAPBPR; TAPASIN-R; tapasin-like; TAP-binding protein-like; TAP binding protein related; TAP-binding protein-related protein; TAPBP-R;
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