Anti-TACC3 monoclonal antibody (DMABT-H12554)

Mouse anti-Human TACC3 monoclonal antibody for WB, IHC, sELISA, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG3
Clone
7D5
Species Reactivity
Human, Rat
Immunogen
TACC3 (NP_006333,2a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
TACC3; transforming, acidic coiled-coil containing protein 3; transforming acidic coiled-coil-containing protein 3; ERIC1; ERIC-1; MGC117382
Entrez Gene ID
UniProt ID

Product Background


Gene summary
TACC3 (Transforming Acidic Coiled-Coil Containing Protein 3) is a Protein Coding gene. Diseases associated with TACC3 include gliosarcoma and giant cell glioblastoma. Among its related pathways are RNA transport and Notch Signaling Pathways. GO annotations related to this gene include protein domain specific binding. An important paralog of this gene is TACC2. This gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This protein may also play a role in growth a differentiation of certain cancer cells.
Antigen Description
Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). May be involved in the control of cell growth and differentiation. May contribute to cancer. Transforming acidic coiled-coil-containing protein 3 is a protein that in humans is encoded by the TACC3 gene. 0The function about TACC3 antigen include protein domain specific binding.
Pathway
Aurora A signaling, organism-specific biosystem; RNA transport, organism-specific biosystem; RNA transport, conserved biosystem.

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