Human SORD blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-Sorbitol Dehydrogenase antibody

Target

Sorbitol Dehydrogenase

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010]

Function

L-iditol 2-dehydrogenase activity; L-iditol 2-dehydrogenase activity; NAD binding; carbohydrate binding; zinc ion binding; zinc ion binding;

Synonyms

SORD; sorbitol dehydrogenase; SORD1; HEL-S-95n; L-iditol 2-dehydrogenase; epididymis secretory sperm binding protein Li 95n;