Specificity
Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver.
Tag/Conjugate
Unconjugated
SequenceSimilarities
Belongs to the serine/threonine dehydratase family.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Antigen Description
Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.
Function
ATP binding; ATP binding; D-serine ammonia-lyase activity; L-serine ammonia-lyase activity; PDZ domain binding; calcium ion binding; glycine binding; magnesium ion binding; protein homodimerization activity; protein homodimerization activity; pyridoxal ph
Synonyms
SRR; serine racemase; ILV1; ISO1; D-serine dehydratase; L-serine dehydratase; D-serine ammonia-lyase; L-serine ammonia-lyase;
Citations
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COA
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