This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]
Function
GTP binding; protein binding;
Synonyms
SEPT1; septin 1; LARP; SEP1; DIFF6; PNUTL3; septin-1; peanut-like protein 3; serologically defined breast cancer antigen NY-BR-24; differentiation 6 (deoxyguanosine triphosphate triphosphohydrolase);
Citations
Publication ()
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