Product Overview
Blocking/Immunizing peptide for anti-SULF2 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008]
Function
N-acetylglucosamine-6-sulfatase activity; N-acetylglucosamine-6-sulfatase activity; arylsulfatase activity; arylsulfatase activity; calcium ion binding; hydrolase activity;
Synonyms
SULF2; sulfatase 2; extracellular sulfatase Sulf-2; HSULF 2; KIAA1247; SULF 2; HSULF-2; FLJ44488; FLJ90554; MGC126411; DKFZp313E091;
Citations
Publication ()
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