Product Overview
Blocking/Immunizing peptide for anti-STX1A/STX1B antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Function
ATP-dependent protein binding; SNAP receptor activity; SNARE binding; calcium channel inhibitor activity; calcium-dependent protein binding; glycoprotein binding; myosin head/neck binding; protein N-terminus binding; protein binding; protein binding, brid
Synonyms
STX1A; syntaxin 1A (brain); STX1; HPC-1; P35-1; SYN1A; syntaxin-1A; neuron-specific antigen HPC-1;
Citations
Publication ()
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