Anti-SRSF5 monoclonal antibody, clone 3D9

Antibody Isotype

IgM

Clone

3D9

Species Reactivity

Human

Immunogen

SFRS5 (AAH18823. 1, 1 aa ~ 273 aa) full-length recombinant protein with GST tag.

Conjugate

Alternative Names

HRS; SFRS5; SRP40; serine/arginine-rich splicing factor 5; SR splicing factor 5; delayed-early protein HRS; pre-mRNA-splicing factor SRP40; splicing factor, arginine/serine-rich 5

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein have been found for this gene.Mouse monoclonal antibody raised against a full-length recombinant SFRS5.

Pathway

Cleavage of Growing Transcript in the Termination Region, organism-specific biosystem; Formation and Maturation of mRNA Transcript, organism-specific biosystem; Gene Expression, organism-specific biosystem; Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem; RNA polymerase II Transcription, organism-specific biosystem; RNA polymerase II Transcription Termination, organism-specific biosystem