Yeast Aha1 [His] (DAG3202)

Yeast Aha1 [His], recombinant protein expressed in E. coli

Product Overview
Recombinant Yeast Aha1, His-tagged
Nature
Recombinant
Tag/Conjugate
His
Procedure
None
Purity
> 95%
Concentration
1.8mg/mL
Buffer
25mM Tris buffer pH72, 150mM NaCl, 0.1mM DTT in 50% glycerol
Preservative
None
Storage
2-8°C short term, -20°C long term
Introduction
Aha1 is a member of the Hsp90 cochaperone family, and is thought to stimulate Hsp90 ATPase activity by competing with p23 and other co-chaperones for Hsp90 binding. It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/Hsp90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors.
Keywords
AHSA2; AHA1; activator of heat shock 90kDa protein ATPase homolog 2 (yeast); Yeast Aha1; SHSA1; HspC322; p38; Aha1

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