This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. [provided by RefSeq, Jul 2008]
Function
DNA binding; core promoter sequence-specific DNA binding; protein binding; sequence-specific DNA binding transcription factor activity;
Synonyms
SOX1; SRY (sex determining region Y)-box 1; transcription factor SOX-1; SRY related HMG box gene 1; SRY-related HMG-box gene 1;
Citations
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