Rabbit Anti-Human SNX10 (a.a. 124-201) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

Recombinant human SNX10 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 124-201 aa of BC034992

Conjugate

Application Notes

WB: 1:1000-1:8000
IHC: 1:50-1:500

General Notes

This product (Catalog No. CABT-BL3401) is a rabbit-derived polyclonal antibody raised against human SNX10, targeting the amino acid region 124–201 of the protein. This antibody exhibits cross-reactivity with Human SNX10 from mouse and rat. It has been affinity purified by Protein A. Sorting nexins are a diverse group of cytoplasmic and membrane-associated proteins classified by the presence of a phospholipid-binding motif PX domain (PMID:12461558). They are involved in endocytosis and protein trafficking. Mutations in SNX10 (Sorting nexin-10) have been found to account for approximately 4% of all human autosomal recessive osteopetrosis (ARO) that is a genetically heterogeneous disorder caused by reduced bone resorption by osteoclasts (PMID: 23280965; PMID: 28592808).
CABT-BL3401 is suitable for use in Western blot (WB) (1:1,000–1:8,000), IHC (1:50–1:500) applications.
CABT-BL3401 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

Sorting nexin-10; sorting nexin 10

Entrez Gene ID

UniProt ID