This gene is a member of the potassium-dependent sodium/calcium exchanger family and encodes an intracellular membrane protein with 2 large hydrophilic loops and 2 sets of multiple transmembrane-spanning segments. Sequence variation in this gene has been associated with differences in skin pigmentation. [provided by RefSeq, Jul 2008]
Function
antiporter activity; symporter activity;
Synonyms
SLC24A5; solute carrier family 24, member 5; sodium/potassium/calcium exchanger 5; JSX; ion transporter JSX; Na(+)/K(+)/Ca(2+)-exchange protein 5; solute carrier family 24 (sodium/potassium/calcium exchanger), member 5; NCKX5; SHEP4;
Citations
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