SLC17A4 (NP_005486, 56 aa ~ 132 aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
Target
Alternative Names
solute carrier family 17 (sodium phosphate), member 4; MGC129623; KIAA2138; Na/PO4 cotransporter; Solute carrier family 17 member 4; putative small intestine sodium-dependent phosphate transport protein; KAIA2138; OTTHUMP00000016125
Phosphate homeostasis is maintained by regulating intake, intestinal absorption, bone deposition and resorption, and renal excretion of phosphate. The central molecule in the control of phosphate excretion from the kidney is the sodium/phosphate cotransporter NPT1 (SLC17A1; MIM 182308), which is located in the renal proximal tubule. NPT1 uses the transmembrane electrochemical potential gradient of sodium to transport phosphate across the cell membrane. SLC17A4 is a similar sodium/phosphate cotransporter in the intestinal mucosa that plays an important role in the absorption of phosphate from the intestine (summary by Shibui et al., 1999Mouse monoclonal antibody raised against a partial recombinant SLC17A4.
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