Species Reactivity: Mouse, Rat, Human, Dog, Cow, Sheep
Summary
Specifications
Antibody Isotype
IgG
Species Reactivity
Mouse; Rat; Human; Dog; Cow; Sheep
Immunogen
KLH conjugated synthetic peptide derived from human SKOR2: 871-970/1001
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 1:100-500 IHC-F: 1:100-500 IF: 1:100-500
General Notes
This product (Catalog No. CABT-BL3298) is a rabbit-derived IgG polyclonal antibody raised against human SKOR2, targeting the amino acid region 871–970 of the protein. This antibody exhibits cross-reactivity with SKOR2 from mouse, rat, dog, cow, and sheep. It has been affinity purified by protein A. Enables SMAD binding activity and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transforming growth factor beta receptor signaling pathway. Located in cytoplasm and nucleus. CABT-BL3298 is suitable for use in IHC-P (1:100–1:500), IHC-F (1:100–1:500), IF (immunofluorescence) (1:100–1:500) applications. CABT-BL3298 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
CORL2; Functional smad suppressing element 18; Functional Smad-suppressing element on chromosome 18; Fussel-18; FUSSEL18; Ladybird homeobox corepressor 1-like protein; LBX1 corepressor 1-like protein; SKI family transcriptional corepressor 2; SKOR2; SKOR2_HUMAN
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