Product Overview
Blocking/Immunizing peptide for anti-SFRP4 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression. [provided by RefSeq, Jul 2008]
Function
PDZ domain binding; Wnt-activated receptor activity; Wnt-protein binding;
Synonyms
SFRP4; secreted frizzled-related protein 4; FRP 4; FRPHE; frpHE; sFRP-4; frizzled protein, human endometrium; FRP-4; MGC26498;
Citations
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Etheridge, SL; Spencer, GJ; et al. Expression profiling and functional analysis of Wnt signaling mechanisms in mesenchymal stem cells. STEM CELLS 22:849-860(2004).
Horvath, LG; Henshall, SM; et al. Membranous expression of secreted frizzled-related protein 4 predicts for good prognosis in localized prostate cancer and inhibits PC3 cellular proliferation in vitro. CLINICAL CANCER RESEARCH 10:615-625(2004).
COA
Certificate of Analysis
