Human SCN5A blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-SCN5A antibody

Target

SCN5A

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Function

calmodulin binding; ion channel activity; protein binding; voltage-gated ion channel activity; voltage-gated sodium channel activity;

Synonyms

SCN5A; sodium channel, voltage-gated, type V, alpha subunit; CMD1E, sodium channel, voltage gated, type V, alpha (long QT syndrome 3); sodium channel protein type 5 subunit alpha; CDCD2; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; long QT syndrome 3; LQT3; Nav1.5; PFHB1; SSS1; voltage-gated sodium channel subunit alpha Nav1.5; sodium channel protein cardiac muscle subunit alpha; cardiac tetrodotoxin-insensitive voltage-dependent sodium channel alpha subunit; VF1; CMD1E;