Anti-SC5DL (aa 72-121) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide within residues: QVRREIKFTV QALPWISILT VALFLLEIRG YSKLHDDLGE FPYGLFELVV, corresponding to N terminal amino acids 72-121 of Human SC5DL.

Conjugate

Application Notes

WB: 1μg/ml

Alternative Names

SC5DL; sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like; sterol C5 desaturase (ERG3 delta 5 desaturase homolog, fungal) like , sterol C5 desaturase (fungal ERG3, delta 5 desaturase) like; lathosterol oxidase; Lathosterol oxidase; S5DES; 3beta hydroxysteroid delta5 desaturase; C 5 sterol desaturase; Delta 5 desaturase like; Delta sterol 5 desaturase; ERG3; Fungal ERG3; Lathosterol 5 desaturase; MGC93101; SC5D; Sterol C5 desaturase (ERG3 delta 5 desaturase homolog, S. cerevisiae) like; Sterol C5 desaturase; C-5 sterol desaturase; lathosterol 5-desaturase; lathosterol dehydrogenase; delta-sterol 5-desaturase; fungal ERG3, delta-5-desaturase-like; 3beta-hydroxysteroid-delta5-desaturase; ERG3; SC5D; S5DES;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes an enzyme of cholesterol biosynthesis. The encoded protein catalyzes the conversion of lathosterol into 7-dehydrocholesterol. Mutations in this gene have been associated with lathosterolosis. Alternatively spliced transcript variants encoding the same protein have been described.

Pathway

Cholesterol Biosynthesis, organism-specific biosystem; Cholesterol biosynthesis, organism-specific biosystem; Cholesterol biosynthesis, FPP => cholesterol, organism-specific biosystem; Cholesterol biosynthesis, FPP => cholesterol, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Steroid biosynthesis, organism-specific biosystem; Steroid biosynthesis, conserved biosystem; cholesterol biosynthesis I, con