Human SF3B3 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-SAP130/SF3B3 antibody

Target

SAP130 / SF3B3

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. [provided by RefSeq, Jul 2008]

Function

nucleic acid binding;

Synonyms

SF3B3; splicing factor 3b, subunit 3, 130kDa; splicing factor 3b, subunit 3, 130kD; splicing factor 3B subunit 3; KIAA0017; RSE1; SAP130; SF3b130; SAP 130; spliceosome-associated protein 130; pre-mRNA-splicing factor SF3b 130 kDa subunit; pre-mRNA splicing factor SF3b, 130 kDa subunit; STAF130;