Synthetic S-Adenosyl-homocysteine supplied as liquid.
Target
SAH
Nature
Synthetic
Tag/Conjugate
Unconjugated
Concentration
1.0 mg/mL
Preservative
None
Storage
2-8°C short term, -20°C long term
Introduction
Staphylococcus aureus alpha Hemolysin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. The toxin self-assembles to form first, a nonlytic oligomeric intermediate, and then, a mushroom-shaped homoheptamer structure. Heptamer oligomerization and pore formation is required for lytic activity.
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