Product Overview
Rotenone, BSA-conjugated
Specificity
Rotenone conjugated with bovine serum albumin (BSA).
Purity
Purity is greater than 95.0% as determined by HPLC analysis and SDS-PAGE
Storage
2-8°C short term, -20°C long term
Reconstitution
Reconstituted in deionized water (250 μg)
Introduction
Rotenone is a colorless-to-red, odorless solid. In solution it is used as a broad spectrum insecticide that works by inhibiting the transfer of electrons from Fe-S centers in Complex I to ubiquinone (see electron transfer chain). This prevents NADH from being converted into usable cellular energy (ATP). Rotenone is commonly used in powdered form to reduce parasitic mites on chickens and other fowl. It also stuns or kills fish and is used to eradicate exotic fish from their non native habitats. It is toxic to humans and other mammals. However, it breaks down when exposed to sunlight and has a short lifetime (a week or less) in the environment.
Keywords
Rotenone; Canex; 5'-beta-rotenone; Barbasco; Deril; Derrin; (-)-cis-rotenone; Foliafume; derrisextract,e.c.(2.5%); ethenyl)[1]benzopyrano[3,4-b]furo[2,3-h]benzopyran-6(6ah)-one
Citations
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Basta, G; Lazzerini, G; et al. At least 2 distinct pathways generating reactive oxygen species mediate vascular cell adhesion molecule-1 induction by advanced glycation end products. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 25:1401-1407(2005).
Kim, DH; Byamba, D; et al. Different characteristics of reactive oxygen species production by human keratinocyte cell line cells in response to allergens and irritants. EXPERIMENTAL DERMATOLOGY 21:99-103(2012).
COA
Certificate of Analysis
