ARHGAPs, such as ARHGAP24, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).[supplied by OMIM, Mar 2008]
Function
Rac GTPase activator activity; protein binding;
Synonyms
ARHGAP24; Rho GTPase activating protein 24; p73; FILGAP; RCGAP72; RC-GAP72; p73RhoGAP; rho GTPase-activating protein 24; rhoGAP of 73 kDa; sarcoma antigen NY-SAR-88; filamin-A-associated RhoGAP; rho-type GTPase-activating protein 24; RAC1- and CDC42-specific GTPase-activating protein of 72 kDa;
Citations
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