Product Overview
Treponema pallidum (TmpA) p41 recombinant protein (a.a. 23-41 and 288-325) containing GST fusion partner. Molecular weight is 32 kDa. Immunoreactive with human T. pallidum positive serum.
Alternative Names
T. pallidum, Treponema pallidum, T. pallidum P41, Syphilis, Treponema Pallidum p41, TmpA, T. pallidum TmpA
Purity
GS-4B Chromatography. Major band and minor smaller bands on 12% PAGE (Coomassie Staining).
Buffer
4 M Urea, 5 mM Tris-HCl, pH 8.0 containing 10 mM DTT, 0.5 mM EDTA, 50% Glycerol.
Storage
Upon receipt, store at -20°C. Avoid multiple/freeze thaw cycles.
Introduction
Treponema pallidum is a gram-negative spirochaete bacterium and is considered to be metabolically crippled. There are at least four known subspecies: T. pallidum pallidum, T. pallidum pertenue, T. pallidum carateum and T. pallidum endemicum. The helical structure of T. pallidum pallidum allows it to move in a corkscrew motion through viscous mediums such as mucus. Treponema pallidum sub sp. pallidum has one of the smallest bacterial genomes at 1.14 million base pairs (Mb) and has limited metabolic capabilities, reflecting its adaptation through genome reduction to the rich environment of mammalian tissue.
Keywords
T. pallidum; Treponema pallidum; T. pallidum P41; Syphilis; Treponema Pallidum p41; TmpA; T. pallidum TmpA
Citations
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