Product Overview
Recombinant HSP70 protein containing 33-114 amino acids was expressed in E. coli and purified by proprietary chromatographic technique.
Tag/Conjugate
Unconjugated
Purity
> 95% pure as determined by 10% PAGE (coomassie staining) and RP-HPLC.
Buffer
20mM PB, 300mM NaCl, and 100mM Imidazole, pH7.5
Storage
Store at -20°C. Avoid repeated freeze/thaw cycles
Introduction
Plasmodium falciparum is a protozoan parasite, one of the species of Plasmodium that cause malaria in humans. It is transmitted by the female Anopheles mosquito. Malaria caused by this species (also called malignant or falciparum malaria) is the most dangerous form of malaria, with the highest rates of complications and mortality. As of 2006, there were an estimated 247 million human malarial infections (98% in Africa, 75% being 5 years or younger). It is much more prevalent in sub-Saharan Africa than in other regions of the world; in most African countries, more than 75% of cases were due to P. falciparum, whereas in most other countries with malaria transmission, other, less virulent plasmodial species predominate. Almost all malarial deaths are caused by P. falciparum.
Citations
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