Human HSPB6

Nature

Recombinant

Tag/Conjugate

Unconjugated

Format

Purified, Liquid

Concentration

Lotspecific (BCA method)

Buffer

20mMTris/acetate, pH 7.6 containing 10mM NaCl, 0.1mM EDTA, 0.1mM PMSF and 15mMbetamercaptoethanol

Preservative

None

Storage

2-8°C short term, -20°C long term

Introduction

HSPB6 (heat shock protein, alpha-crystallin-related, B6) is a protein-coding gene. Diseases associated with HSPB6 include hereditary cerebral hemorrhage with amyloidosis , and cerebral hemorrhage. GO annotations related to this gene include structural constituent of eye lens and protein homodimerization activity. An important paralog of this gene is HSPB1.

Antigen Description

Heatshock proteins (HSP) are a class of functionally related proteins involved inthe folding and unfolding of other proteins. Their expression is increasedwhen cells are exposed to elevated temperatures or other stress. Thisincrease in expression is transcriptionally regulated. The dramaticupregulation of the heat shock proteins is a key part of the heat shockresponse and is induced primarily by heat shock factor (HSF). HSPs are foundin virtually all living organisms, from bacteria to humans.

Keywords

HSPB6; heat shock protein, alpha-crystallin-related, B6; p20; Hsp20; heat shock protein beta-6; heat shock 20-kDa protein; heat shock 20 kDa-like protein p20;