C-terminal 6xHis tagged VP4 region of HAV capsid protein (a.a. 6-245)
Nature
Recombinant
Tag/Conjugate
His
Purity
> 95%, based on SDS PAGE
Format
Each vial contains 100 μg of lyophilized protein in PBS with 8M Urea.
Preservative
None
Storage
2-8°C short term, -20°C long term
Introduction
Hepatitis A Virus (HAV) is a 27nm nonenveloped, spherical, positive stranded RNA virus, classified within the genus hepatovirus of the picornavirus family and is among the smallest and structurally simplest of the RNA animal viruses. A single large polyprotein is expressed from a large open reading frame extending through most of the genomic RNA. This polyprotein is subsequently cleaved by a viral protease (3Cpro) to form three (possibly four) capsid proteins and several nonstructural proteins. HAV genomic replication occurs exclusively in the cytoplasm of the infected hepatocyte by a mechanism involving an RNA-dependent RNA polymerase.
Keywords
HAV; HAV Ag; HAV VP3; Hepatitis A Virus VP3; Hep A; Hepatitis A Virus protein; Picornaviridae; Hepatoviru
Citations
Publication ()
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